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      【中药名路路通

      【别名】枫实、枫木上球、枫香果、枫果、枫树球、狼眼、九空子、狼目、聂子。

      【英文名】Liquidambaris Fructus

      【药用部位】金缕梅科植物枫香Liquidambar formosana Hance.的成熟果序。

      【植物形态】乔木,高达40米。树皮灰褐色,粗糙,有皮孔。单叶互生,叶片宽卵形,常3裂,幼枝及萌发枝的叶多为掌状5裂,上面深绿色,下面淡绿色;叶柄长3~7厘米;托叶线形,早落。花单性,雌雄同株;雄花为柔荑花序,无花被,雄蕊多数,花丝不等长;雌花为球形的头状花序,直径1.5厘米,有花23~43朵,花序梗长,萼齿5,钻形,无花瓣,子房半下位,2室,胚乳多数,花柱2,柱头弯曲。蒴果多数集生成头状球形果序,直径2.5~4.5厘米,表面有由宿存花柱及子房周围的苞片变成的刺状物,蒴果长椭圆形,下部藏于花序轴内,成熟时顶孔开裂。种子有发育不完全和发育完全两型,前者占多数,多角形,细小,黄棕色,后者长圆形而扁,具翅,褐色。花期3~4月,果期9~10月。

      【产地分布】生于平原及丘陵地带。分布于我国华东、华南、西南等地。

      【采收加工】冬季果实成熟后采收,除去杂质,干燥。

      【药材性状】聚花果,由多数小蒴果集合而成,球形,直径2~3厘米。基部有总果梗。表面灰棕色或棕褐色,有多数尖刺及喙状小钝刺,长0.5~1厘米,常折断,小蒴果顶部开裂,呈蜂窝状小孔。体轻,质硬,不易破开。气微,味淡。

      【性味归经】性平,味苦。归肝经肾经

      【功效与作用】祛风活络,利水通经。属祛风湿药下属分类的祛风湿强筋骨药。

      【临床应用】用量5~9克,煎服。用治关节痹痛、麻木拘挛、水肿胀满、乳少经闭。

      【药理研究】抗炎;保肝。药理实验表明,路路通有明显促进大鼠“甲醛化”关节炎肿胀消退和治疗蛋清性关节炎的功效与作用。

      【化学成分】路路通含挥发油、黄酮类、酚类、有机酸及糖类。此外,尚含齐墩果酮酸甲酯、3-表齐墩果酸甲酯、3-表齐墩果酸甲酯,挥发油中含有β-松油烯、β-蒎烯、柠檬烯、α-松油烯等成分。另含熊果酸、28-去甲齐墩果酮酸、苏合香素、齐墩果酸、氧化丁香烯、a-榄香烯、环氧苏合香素、路路通内酯等成分。

      【使用禁忌】阴虚、月经过多及孕妇禁服。

      【配伍药方】①治癣:路路通10个(烧存性),白砒0.15克。共末,香油搽。(《纲目拾遗》引《德胜堂方》)

      ②治荨麻疹:路路通500克,煎浓汁。每日3次,每次18克。空心服。(《湖南药物志》)

      ③治耳内流黄水:路路通15克。煎服。(《浙江民间草药》)

      ④治过敏性鼻炎:路路通12克,苍耳子防风各9克,辛夷白芷各6克。水煎服。(《中药临床应用》)

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